| AMG S 65 V12 • 612 HP • SPEEDSHIFT | 612 HP | 4.4 sec | 250 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 600 V12 • 500 HP • 5G-TRONIC | 500 HP | 4.8 sec | 250 km/h | 5-speed automatic | Petrol (Gasoline) |
| AMG S 55 V8 • 500 HP • 5G-TRONIC | 500 HP | 4.8 sec | 250 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 500 V8 • 306 HP • 7G-TRONIC | 306 HP | 6.3 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| S 500 V8 • 306 HP • 5G-TRONIC | 306 HP | 6.5 sec | 250 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 430 V8 • 279 HP • 4MATIC 5G-TRONIC | 279 HP | 7.4 sec | 250 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 430 V8 • 279 HP • 5G-TRONIC | 279 HP | 6.9 sec | 250 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 430 V8 • 279 HP • 7G-TRONIC | 279 HP | 7.1 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| S 400 CDI V8 • 250 HP • 5G-TRONIC | 250 HP | 7 sec | 249 km/h | 5-speed automatic | Diesel |
| S 350 V6 • 245 HP • 5G-TRONIC | 245 HP | 7.3 sec | 246 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 350 V6 • 245 HP • 4MATIC 5G-TRONIC | 245 HP | 7.9 sec | 242 km/h | 5-speed automatic | Petrol (Gasoline) |
| S 320 CDI • 204 HP • 5G-TRONIC | 204 HP | 8.2 sec | 235 km/h | 5-speed automatic | Diesel |