| E 500 V8 • 408 HP • 7G-TRONIC PLUS | 408 HP | 4.8 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 400 V6 3.5 • 333 HP • 7G-TRONIC PLUS | 333 HP | 5.2 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 400 V6 3.0 • 333 HP • 7G-TRONIC PLUS | 333 HP | 5.2 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 350 V6 • 306 HP • 7G-TRONIC PLUS | 306 HP | 6.2 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 350 V6 • 306 HP • 4MATIC 7G-TRONIC PLUS | 306 HP | 6.5 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 320 V6 • 272 HP • 7G-TRONIC PLUS | 272 HP | 6.6 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 350 BlueTEC V6 • 258 HP • 9G-TRONIC | 258 HP | 6.2 sec | 250 km/h | 9-speed automatic | Diesel |
| E 350d V6 • 258 HP • 9G-TRONIC | 258 HP | 6.2 sec | 250 km/h | 9-speed automatic | Diesel |
| E 300 V6 • 252 HP • 7G-TRONIC PLUS | 252 HP | 6.9 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 350 BlueTEC V6 • 252 HP • 7G-TRONIC PLUS | 252 HP | 6.4 sec | 250 km/h | 7-speed automatic | Diesel |
| E 250 • 211 HP • 7G-TRONIC PLUS | 211 HP | 7.1 sec | 250 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 250 CDI • 204 HP | 204 HP | 7.4 sec | 250 km/h | 6-speed manual | Diesel |
| E 250 BlueTEC • 204 HP | 204 HP | 7.4 sec | 250 km/h | 6-speed manual | Diesel |
| E 250d • 204 HP | 204 HP | 7.4 sec | 250 km/h | 6-speed manual | Diesel |
| E 250d • 204 HP • 9G-TRONIC | 204 HP | 7.3 sec | 250 km/h | 9-speed automatic | Diesel |
| E 250 CDI • 204 HP • 7G-TRONIC PLUS | 204 HP | 7.3 sec | 247 km/h | 7-speed automatic | Diesel |
| E 250 BlueTEC • 204 HP • 9G-TRONIC | 204 HP | 7.3 sec | 250 km/h | 9-speed automatic | Diesel |
| E 200 • 184 HP | 184 HP | 8 sec | 240 km/h | 6-speed manual | Petrol (Gasoline) |
| E 200 • 184 HP • 7G-TRONIC PLUS | 184 HP | 7.8 sec | 240 km/h | 7-speed automatic | Petrol (Gasoline) |
| E 220d • 170 HP | 170 HP | 8.5 sec | 235 km/h | 6-speed manual | Diesel |
| E 220 BlueTEC • 170 HP • 9G-TRONIC | 170 HP | 8.1 sec | 237 km/h | 9-speed automatic | Diesel |
| E 220 CDI • 170 HP | 170 HP | 8.5 sec | 235 km/h | 6-speed manual | Diesel |
| E 220 CDI • 170 HP • 7G-TRONIC PLUS | 170 HP | 8.3 sec | 234 km/h | 7-speed automatic | Diesel |
| E 220 BlueTEC • 170 HP | 170 HP | 8.5 sec | 235 km/h | 6-speed manual | Diesel |
| E 220d • 170 HP • 9G-TRONIC | 170 HP | 8.1 sec | 237 km/h | 9-speed automatic | Diesel |