| AMG C 63 S V8 • 510 HP • MCT | 510 HP | 4 sec | 290 km/h | 9-speed automatic | Petrol (Gasoline) |
| AMG C 63 V8 • 476 HP • MCT | 476 HP | 4.1 sec | 250 km/h | 9-speed automatic | Petrol (Gasoline) |
| AMG C 43 V6 • 390 HP • 4MATIC TCT | 390 HP | 4.7 sec | 250 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 400 V6 • 333 HP • 4MATIC 9G-TRONIC | 333 HP | 4.9 sec | 250 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 300e • 320 HP • EQ Power 9G-TRONIC | 320 HP | 5.4 sec | 250 km/h | 9-speed automatic | Petrol / electricity |
| C 300e • 320 HP • EQ Power 4MATIC 9G-TRONIC | 320 HP | 5.4 sec | 250 km/h | 9-speed automatic | Petrol / electricity |
| C 300de • 306 HP • EQ Power 9G-TRONIC | 306 HP | 5.6 sec | 250 km/h | 9-speed automatic | Diesel / electricity |
| C 300 • 258 HP • EQ Boost 9G-TRONIC | 258 HP | 5.9 sec | 250 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 300 • 258 HP • EQ Boost 4MATIC 9G-TRONIC | 258 HP | 5.7 sec | 250 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 300d • 245 HP • 9G-TRONIC | 245 HP | 5.9 sec | 250 km/h | 9-speed automatic | Diesel |
| C 300d • 245 HP • 4MATIC 9G-TRONIC | 245 HP | 5.7 sec | 250 km/h | 9-speed automatic | Diesel |
| C 220d • 194 HP • 4MATIC 9G-TRONIC | 194 HP | 6.9 sec | 233 km/h | 9-speed automatic | Diesel |
| C 220d • 194 HP • 9G-TRONIC | 194 HP | 6.9 sec | 240 km/h | 9-speed automatic | Diesel |
| C 200 • 184 HP • EQ Boost 4MATIC 9G-TRONIC | 184 HP | 8.1 sec | 234 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 200 • 184 HP • EQ Boost 9G-TRONIC | 184 HP | 7.7 sec | 239 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 200d • 160 HP | 160 HP | 8.5 sec | 226 km/h | 6-speed manual | Diesel |
| C 180 1.6 • 156 HP | 156 HP | 8.2 sec | 225 km/h | 6-speed manual | Petrol (Gasoline) |
| C 180 1.6 • 156 HP • 9G-TRONIC | 156 HP | 8.3 sec | 225 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 180 1.5 • 156 HP • 9G-TRONIC | 156 HP | 8.6 sec | 223 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 200d • 150 HP • 9G-TRONIC | 150 HP | 8.1 sec | 222 km/h | 9-speed automatic | Diesel |
| C 160 • 129 HP • 9G-TRONIC | 129 HP | 10.3 sec | 208 km/h | 9-speed automatic | Petrol (Gasoline) |
| C 160 • 129 HP | 129 HP | 9.6 sec | 216 km/h | 6-speed manual | Petrol (Gasoline) |
| C 180d • 122 HP | 122 HP | 10 sec | 207 km/h | 6-speed manual | Diesel |